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	<title>determine &#8211; USA NEWS LIVE</title>
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	<title>determine &#8211; USA NEWS LIVE</title>
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		<title>Can I determine rules about what&#8217;s left on the grave?</title>
		<link>https://bloggingthree.soflytech.com/2025/03/can-i-determine-rules-about-whats-left-on-the-grave/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Sun, 09 Mar 2025 20:45:19 +0000</pubDate>
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		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=25946</guid>

					<description><![CDATA[I write to ask if there are rules of etiquette to go to a loved one within the cemetery. We go commonly. I decorate the realm in front of your stone with vacation or seasonally adequate decorations. Other relations and friends also visit and most leave small jewelry or fresh flowers, which I pick up [&#8230;]]]></description>
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<p>I write to ask if there are rules of etiquette to go to a loved one within the cemetery.</p>
<p>We go commonly. I decorate the realm in front of your stone with vacation or seasonally adequate decorations. Other relations and friends also visit and most leave small jewelry or fresh flowers, which I pick up and throw away after they cancel or bring home and produce it to our daughter&#39;s room.</p>
<p>My problem is that a member of the family opens cards that were left for my daughter there and puts all possible low cost decorations round her grave. They recently put decorations directly on their tombstone, which left large spots. We are actually searching for a specialist to remove the damage or your stone has to get replaced.</p>
<p>I&#8217;m besides myself. Here I speak to my daughter to feel closer to her. It took a 12 months for her stone to be set. I took time to decide on exactly the proper etchings and image, and it&#8217;s a stone that corresponds to our beautiful angel.</p>
<p>Would it&#8217;s improper to find out rules for what people can leave and what not when visiting my daughter&#39;s last resting place? Can I tell someone that he now not desires to visit?</p>
<p style="text-align: right">
<p><strong>Better protection</strong>: Please accept my deepest sympathy for the lack of your daughter.</p>
<p>I hope the relative who damaged her tombstone apologized for it and volunteered to pay the services of the skilled cleaner. If not, it is best to suggest it. And while you&#8217;re there, it&#8217;s also possible to explain what sort of memory you might be appropriate for on the grave.</p>
<p>However, understand that you have got the proper to specify your preferences unless there&#8217;s a guard that observes your daughter&#39;s last resting places, there is no such thing as a guarantee that you simply can be respected.</p>
<p><strong>Dear Abby</strong>: We all meet acquaintances and say: &#8220;Let us grab dinner.&#8221; We intend to carry out, but forget.</p>
<p>Some time ago my wife and I made a listing of 10 other couples that we desired to know higher and we organized a bunch meal. We all selected a rotation: On the third Saturday of the month, a pair was to arrange the group in a restaurant.</p>
<p>We don&#39;t meet in December and, yes, sometimes only six couples participate, nevertheless it is commonly all of us. During Covid we collected from Zoom. This is our twenty fifth 12 months and we didn&#39;t miss a month.</p>
<aside class="related right"></aside>
<p>It&#39;s not about eating &#8211; it&#39;s a couple of caring group of friends who share with one another. Abby, I assumed it is advisable to print this to encourage others.</p>
<p style="text-align: right">
<p><strong>Dear host</strong>: I believe the lesson here is that somebody must be proactive and really make plans as an alternative of being satisfied with good intentions.</p>
<p>They all did an infinite man, including them themselves. Loneliness and isolation are serious problems for a lot of.</p>
</p></div>
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		<title>Your surroundings have an effect on how well your medication works &#8211; precisely determine</title>
		<link>https://bloggingthree.soflytech.com/2025/02/your-surroundings-have-an-effect-on-how-well-your-medication-works-precisely-determine/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Sun, 09 Feb 2025 19:34:16 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[determine]]></category>
		<category><![CDATA[impact]]></category>
		<category><![CDATA[medication]]></category>
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		<category><![CDATA[surroundings]]></category>
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		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=24266</guid>

					<description><![CDATA[Your genes play a very important role When determining your size, your hair and eye color and your skin tone, you don&#39;t tell the entire story who you&#8217;re. Your surroundings are incredibly vital to shape your personality, your preferences and dislikes and your health. In fact, their eating regimen, social interactions, exposure to dirt, physical [&#8230;]]]></description>
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<p>Your genes <a href="https://doi.org/10.1038/ng.3285">play a very important role</a> When determining your size, your hair and eye color and your skin tone, you don&#39;t tell the entire story who you&#8217;re. Your surroundings are incredibly vital to shape your personality, your preferences and dislikes and your health. In fact, their eating regimen, social interactions, exposure to dirt, physical activity and education are common <a href="https://doi.org/10.1038/s41588-018-0313-7">Exceed the influence of genetics</a> on lots of the functions they define.</p>
<p>If you learn how your genes and the environment increase your probability of developing asthma, heart disease, cancer, dementia and other diseases, life -changing consequences can have. The area of ​​genomics has made it relatively easy to check quite a lot of genetic variations in reference to the chance of illness each within the hospital and at home.</p>
<p>And lately, science has progress within the detection of the <a href="https://doi.org/10.1101/2023.03.10.23286340">Environmental</a> This risk for several diseases and the determination of possibilities for optimizing treatments based in your personal environmental pollution.</p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#50482f"><img decoding="async" alt="Personal sorted by pills, a variety of tablet bottles and a weekly pill box" class="lazyload" src="https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/645448/original/file-20250129-15-9rsus0.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">The prescription of essentially the most effective treatment of Get-GO can reduce harmful drug reactions.</span><br />
              <span class="attribution"><a class="source" href="https://www.gettyimages.com/detail/photo/sorting-weekly-medication-royalty-free-image/1190823309">Willie B. Thomas/DigitalVision via Getty Images</a></span><br />
            </figcaption></figure>
<p>My work as <a href="https://scholar.google.com/citations?user=9uz8tUgAAAAJ&#038;hl=en">Pharmacologist and toxicologist</a> led me to the creation <a href="https://factor.niehs.nih.gov/2024/10/feature/1-feature-exposomics">Exposomics science</a> &#8211; The examination of all physical, chemical, biological and social aspects that influence their biology. While your genome includes all of the genes that encode your biology, your exposome is an idea that features all of your environmental pollution. As the best way researchers use DNA sequencer to look at genomics, scientists use chemistry and high-tech sensors in exposomics to measure the results of hundreds of environmental aspects on health.</p>
<h2>Medicines don&#39;t all the time work</h2>
<p>For many individuals, standard drug therapies simply don&#8217;t work to treat certain diseases. control <a href="https://www.heart.org/en/health-topics/high-blood-pressure/the-facts-about-high-blood-pressure/resistant-hypertension--high-blood-pressure-thats-hard-to-treat">Blood pressure</a> often requires months of attempt and error. It can take months and even years to find out an appropriate treatment plan <a href="https://www.psychiatrist.com/jcp/inadequate-response-antidepressant-treatment-major">For depression</a>. </p>
<p>Unwanted events attributable to medication <a href="https://www.yalemedicine.org/news/polypharmacy">More than 1 million</a> Visits to emergency rooms yearly within the USA What drives these differences within the drug effects between patients? Is it your genes? Don&#39;t you&#8217;re taking your medication, as prescribed on the premise of unintended effects? Or something else? </p>
<p>As it seems, your environment can have a significant impact on how well certain treatments give you the results you want. Think of the warning signs that advise you, for instance, not drink grapefruit juice while taking a certain medication. This is because a natural chemical in grapefruit inhibits the enzymes that reduce these medication. Some common statins for checking high levels of cholesterol can construct on toxic values, for the reason that chemical in grapefruit juice blocks its normal processing. </p>
<p>Grapefruit shouldn&#8217;t be the one environmental factor that influences the best way they react to their medication. <a href="https://www.epa.gov/chemical-data-reporting/overview-2020-cdr-national-review">Over 8,600 chemicals</a> are utilized in the USA within the United States they usually are exposed to hundreds of those chemicals every single day. It is more likely than not that lots of these chemicals can interact with the medication they take. </p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:100.0%;--background-color:#72916d"><img decoding="async" alt="Diagram of a person surrounded by icons of the various environmental exposures that make up the exposome" class="lazyload" src="https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=600&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=600&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=600&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=754&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=754&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/645443/original/file-20250129-21-lrog13.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=754&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">Their exposome includes quite a lot of aspects.</span><br />
              <span class="attribution"><a class="source" href="https://commons.wikimedia.org/wiki/File:Exposome_nruaux.jpg">Nathalie Ruaux/Wikimedia Commons</a>Present <a class="license" href="http://creativecommons.org/licenses/by-sa/4.0/">CC BY-SA</a></span><br />
            </figcaption></figure>
<p>Some of the chemicals we use to maintain fleas and ticks from pets can actually <a href="https://doi.org/10.1016/S0006-2952(01)00639-6">Increase the values</a> The same enzyme blocked by grapefruit juice, which implies that a statin might be broken down so quickly that it doesn&#8217;t control the increased cholesterol level. </p>
<p><a href="https://wwwn.cdc.gov/tsp/substances/ToxSubstance.aspx?toxid=25">Products from combustion</a> The drug -metabolizing enzymes also can affect organic substance resembling motor exhaust gas and burning wood. Some of those chemicals, called <a href="https://doi.org/10.2174/1389200221999210101233135">Polyaromatic hydrocarbons</a>can inactivate medication for the treatment of asthma. The environmental factor that triggers your asthma can prevent the medication from working to treat work.</p>
<h2>A chemical solution?</h2>
<p>Researchers help to seek out advances in chemistry to seek out out which chemicals are in the best way of treatment. </p>
<p>Your hospital laboratory can already measure dozens of molecules in your blood. Measuring their salt levels can tell the doctors how their kidneys work, levels of cholesterol indicate their risk of heart diseases, and certain enzymes show the health of their liver. These common tests are routinely and useful for nearly every patient.</p>
<p>There are many additional tests that might be used to find out how a certain disease reacts progress or therapy. The hemoglobin -a1c levels determine how well the glucose levels in patients with prediabetes or diabetes are checked. And hundreds of other human diseases have their very own <a href="https://doi.org/10.1093/nar/gky1105">Corresponding biomarker</a>.</p>
<p>In research laboratories, scientists can recognize the existence of hundreds of molecules at the identical time with instruments <a href="https://www.ncbi.nlm.nih.gov/books/NBK589702/">Mass spectrometer</a>. Every chemical in a single sample has a novel mass, and these devices measure these masses in order that scientists can categorize. For this reason, scientists can discover all pesticides, plasticizers, plastics, pollution and other chemicals in a certain sample. You also can measure your individual internal biology, e.g. B. the connections involved within the processing of the food they eat and the hormones that behave. </p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:70.6896551724138%;--background-color:#6c88a5"><img decoding="async" alt="Graphics with a series of vertical blue lines, a y-axis of the ion yield and an X axis of the mass" class="lazyload" src="https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=424&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=424&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=424&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=533&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=533&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/645446/original/file-20250129-15-lrog13.png?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=533&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">A sample mass spectrometry reading of laboratory air. Each peak indicates the presence of a certain connection.</span><br />
              <span class="attribution"><a class="source" href="https://commons.wikimedia.org/wiki/File:Ptr_mass_spectrum_of_lab_air.png">Philipp Sulzer/Wikimedia Commons</a></span><br />
            </figcaption></figure>
<p>In addition, mass spectrometers can <a href="https://doi.org/10.1002/rcm.8235">Measure lively ingredient metabolites</a>. If you&#8217;re taking a drugs, it is often broken all the way down to several different compounds or metabolized. Some of those compounds contribute to the effect of the drug, others are inactive. The evaluation of which metabolites can be found in your body provides information on  process medication and whether the medication that you just take interact. </p>
<p>If you summarize all of those aspects, scientists can examine how their environment can affect the effectiveness of their medication.</p>
<h2>A greater recipe &#8211; for you</h2>
<p>Together with dozens of scientists in lots of institutions, my colleagues and I develop methods to measure all chemicals of their bodies. The project, <a href="https://www.publichealth.columbia.edu/news/research-effort-aims-bring-personalized-medicine-drug-prescriptions">called indipharm</a> &#8211; briefly, for individualized pharmacology &#8211; tools designed to measure a wide selection of medicines, drug metabolites and environmental chemicals at the identical time. </p>
<p>By combining environmental data with genetic information, we hope to enhance how medicinal products work in humans by checking out whether chemicals of their environment or nutrition change the processing of a certain medication. This includes whether the drugs administered are on therapeutic values, how the medication and chemicals interact with one another, and determine whether other variable -intended drug effects influence. This could cause the quantity of prescribed medicines to alter, switch to a different drug and even redesign the medication itself.  </p>
<p>Our team begins with the identification of the biological and biological aspects which might be assembled with metabolic diseases, including obesity and diabetes, along with frequent diseases resembling hypertension, high cholesterol and depression. For example, there may be <a href="https://doi.org/10.1136/bmj-2023-076410">significant differences</a> How well people react to anti-adiposity or anti-diabetes medication, and we hope to seek out out why this may profit from tailor-made treatment.   </p>
<p>Bringing the best medication at the best time at the best time requires a greater understanding of the environmental aspects that influence their functioning. We imagine a future through which a physician can use your genetic and environmental history to seek out one of the best drug treatment that may give you the results you want right from the beginning, which reduces the necessity for attempt and error.</p>
</p></div>
<p><em>image credit : theconversation.com</em></p>
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		<title>Blood tests are currently a one-size-fits-all solution – machine learning can determine exactly what is actually “normal” for every patient</title>
		<link>https://bloggingthree.soflytech.com/2024/12/blood-tests-are-currently-a-one-size-fits-all-solution-machine-learning-can-determine-exactly-what-is-actually-normal-for-every-patient/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Thu, 12 Dec 2024 04:22:19 +0000</pubDate>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[determine]]></category>
		<category><![CDATA[learning]]></category>
		<category><![CDATA[machine]]></category>
		<category><![CDATA[normal]]></category>
		<category><![CDATA[onesizefitsall]]></category>
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		<category><![CDATA[Tests]]></category>
		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=20747</guid>

					<description><![CDATA[If a health care provider has ever ordered you to have a blood test, there may be probability they&#8217;ve done one complete blood countor CBC. One of the The commonest blood tests Billions of CBC tests are performed worldwide every year to diagnose diseases and monitor patients&#39; health. But despite the test&#39;s ubiquity, the best [&#8230;]]]></description>
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<p>If a health care provider has ever ordered you to have a blood test, there may be  probability they&#8217;ve done one <a href="https://medlineplus.gov/lab-tests/complete-blood-count-cbc/">complete blood count</a>or CBC. One of the <a href="https://doi.org/10.1093/ajcp/aqy165">The commonest blood tests</a> Billions of CBC tests are performed worldwide every year to diagnose diseases and monitor patients&#39; health. </p>
<p>But despite the test&#39;s ubiquity, the best way doctors interpret and use it within the clinic is usually lower than ideal. Currently, blood test values ​​are based on uniform reference intervals that don&#8217;t take individual differences under consideration.</p>
<p>I&#8217;m a <a href="https://scholar.google.com/citations?user=e8W2uR0AAAAJ&#038;hl=en&#038;oi=ao">mathematician</a> on the University of Washington School of Medicine, and my team is researching ways to make improvements using computational tools <a href="https://foylab.xyz">clinical blood test</a>. In order to develop higher methods for recording individual patient definitions of “normal” laboratory values, my colleagues and I within the <a href="https://www.massgeneral.org/pathology/research/higgins-lab">Higgins Laboratory</a> studied at Harvard Medical School <a href="https://www.nature.com/articles/s41586-024-08264-5">20 years of blood tests</a> of tens of hundreds of patients on the East and West Coasts.</p>
<p>In our newly published study, we used machine learning to discover healthy people <a href="https://www.nature.com/articles/s41586-024-08264-5">Blood count areas</a> for individual patients and predict their risk of future disease.</p>
<h2>Clinical tests and complete blood count</h2>
<p>Many people commonly view clinical tests as purely diagnostic tests. For example, a COVID-19 or pregnancy test is either positive or negative and provides details about whether you&#8217;ve gotten a certain disease. However, most tests don&#8217;t work this fashion. Instead, they measure a biological characteristic of your body <a href="https://doi.org/10.3389/fphys.2020.00200">regulates constantly up and down</a> stay inside certain limits. </p>
<p>Your complete blood count can be a continuum. The CBC test creates an in depth profile of your blood cells &#8211; equivalent to what number of red blood cells, platelets and white blood cells are in your blood. These markers are used day by day in just about all areas of medication. </p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.44562334217507%;--background-color:#aa6553"><img decoding="async" alt="Blood tube on top of lab results printout" class="lazyload" src="https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=399&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=399&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=399&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=501&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=501&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/637680/original/file-20241210-15-vcbw8e.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=501&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">You probably had a blood count test at your annual checkup.</span><br />
              <span class="attribution"><a class="source" href="https://www.gettyimages.com/detail/photo/laboratory-series-royalty-free-image/172685917">peepo/E+ via Getty Images</a></span><br />
            </figcaption></figure>
<p>For example, <a href="https://medlineplus.gov/ency/imagepages/19510.htm">hemoglobin</a> is an iron-containing protein that permits your red blood cells to hold oxygen. If your hemoglobin level is low, it could indicate that you simply are <a href="https://www.nhlbi.nih.gov/health/anemia/iron-deficiency-anemia">Iron deficiency</a>.</p>
<p><a href="https://medlineplus.gov/plateletdisorders.html">Platelets</a> are cells that help form blood clots and stop bleeding. If yours <a href="https://www.ncbi.nlm.nih.gov/books/NBK542208/">The platelet count is low</a>This may mean that you&#8217;ve gotten internal bleeding and your body is using platelets to form blood clots to plug the wound. </p>
<p><a href="https://medlineplus.gov/lab-tests/white-blood-count-wbc/">White blood cells</a> are a part of your immune system. If your white blood cell count is high, it could mean you&#8217;ve gotten an infection and your body is producing more of those cells to fight it off. </p>
<h2>Normal ranges and reference intervals</h2>
<p>But all of this raises the query: What actually counts as too high or too low in a blood test? </p>
<p>Traditionally, doctors determine so-called reference intervals by conducting a blood test on a variety of healthy people. Typically they take the center 95% of those healthy values ​​and call them “normal,” with anything above or below being too low or too high. These normal ranges are used almost in every single place in medicine. </p>
<p>However, reference intervals face a significant challenge: what&#8217;s normal for you might not be normal for another person. </p>
<p>Almost all blood count markers are hereditary, i.e. yours <a href="https://doi.org/10.1016/j.cell.2020.08.008">Genetics and environment</a> To a big extent, determine what the healthy value for every marker can be for you. </p>
<p>For example, on the population level a <a href="https://www.ucsfhealth.org/medical-tests/platelet-count">normal platelet count</a> is between 150 and 400 billion cells per liter of blood. However, your body will want to maintain a platelet count of 200 &#8211; a price called your set point. This means your normal range may only be 150 to 250. </p>
<p>Differences between a patient&#39;s true normal range and the population-based reference interval <a href="https://doi.org/10.1038/s41467-024-47804-5">may cause problems</a> for doctors. They could also be less prone to diagnose a disease in case your set point is way from a limit. Conversely, in case your setpoint is just too near a limit, they could perform unnecessary testing.</p>
<figure>
<p><iframe title="Introduction to lab values and normal ranges | Health &amp; Medicine | Khan Academy" width="1170" height="658" src="https://www.youtube.com/embed/_mGszRbve9s?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p><figcaption><span class="caption">Laboratory tests are interpreted using reference intervals.</span></figcaption></figure>
<h2>Define what&#8217;s normal for you</h2>
<p>Fortunately, many patients have blood work done yearly <a href="https://doi.org/10.1001/archinte.165.12.1347">Routine examinations</a>. Using machine learning models, my team and I were in a position to make estimates <a href="https://www.nature.com/articles/s41586-024-08264-5">Blood count goal values</a> for over 50,000 patients based on their clinic visit history. This allowed us to look at how the body regulates these set points and to check whether we are able to develop higher ways to personalize laboratory test values. </p>
<p>Over several a long time now we have found that the person normal ranges are approx <a href="https://www.nature.com/articles/s41586-024-08264-5">3 times smaller</a> than on the population level. For example, while the &#8220;normal&#8221; range for white blood cell count is around 4.0 to 11.0 billion cells per liter of blood, now we have found that the majority people&#39;s individual ranges are much narrower, closer to 4.5 to 7 or 7.5 to 10. When We used these goal values ​​to interpret latest test results. They have helped improve the diagnosis of diseases equivalent to iron deficiency, chronic kidney disease and hypothyroidism. We were in a position to detect when an individual&#39;s result was outside their smaller personal range, potentially indicating an issue, even when the result was inside the conventional range for the final population.</p>
<p>The set points themselves were strong <a href="https://www.nature.com/articles/s41586-024-08264-5">Indicators of future risks</a> to develop an illness. For example, patients with high white blood cells were more prone to develop type 2 diabetes in the long run. Additionally, they were almost twice as prone to die from any cause as similar patients with low white blood cell counts. Other blood count markers were also strong predictors of future morbidity and mortality risk.</p>
<p>In the long run, physicians may have the opportunity to make use of thresholds to enhance disease screening and interpretation of recent test results. This is an exciting avenue for personalized medicine: defining what exactly “healthy” means to you based on your individual medical history.</p>
</p></div>
<p><em>image credit : theconversation.com</em></p>
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		<title>Why water costs for poor black voters in Detroit could determine whether Kamala Harris wins or loses in Michigan</title>
		<link>https://bloggingthree.soflytech.com/2024/09/why-water-costs-for-poor-black-voters-in-detroit-could-determine-whether-kamala-harris-wins-or-loses-in-michigan/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Thu, 19 Sep 2024 18:12:10 +0000</pubDate>
				<category><![CDATA[Politics]]></category>
		<category><![CDATA[black]]></category>
		<category><![CDATA[costs]]></category>
		<category><![CDATA[determine]]></category>
		<category><![CDATA[Detroit]]></category>
		<category><![CDATA[Harris]]></category>
		<category><![CDATA[Kamala]]></category>
		<category><![CDATA[loses]]></category>
		<category><![CDATA[Michigan]]></category>
		<category><![CDATA[Poor]]></category>
		<category><![CDATA[voters]]></category>
		<category><![CDATA[water]]></category>
		<category><![CDATA[wins]]></category>
		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=15194</guid>

					<description><![CDATA[The threat of violence was within the air on the TCF Center in Detroit on November 5, 2020, after former President Donald Trump claimed that poll employees in the town duplicated ballots and that there was an unexplained delay within the delivery of ballots for counting. Both Claims were later refuted. Encouraged by Trump’s rhetoric, [&#8230;]]]></description>
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<p>The threat of violence was within the air on the TCF Center in Detroit on November 5, 2020, after former <a href="https://www.fox2detroit.com/news/trump-lambastes-detroit-in-ballot-counting-criticism-calling-it-corrupt">President Donald Trump claimed</a> that poll employees in the town duplicated ballots and that there was an unexplained delay within the delivery of ballots for counting. </p>
<p>Both <a href="https://apnews.com/article/fact-checking-9961890106">Claims were later refuted</a>. </p>
<p>Encouraged by Trump’s rhetoric, dozens of predominantly white Republican Trump supporters knocked on the doors and windows of the vote counting center, chanting: “<a href="https://www.pbs.org/newshour/politics/trump-supporters-demand-michigan-vote-center-stop-the-count">Stop the count</a>!”</p>
<p>But Detroit&#39;s poll employees, most of them black, were capable of count the votes. <a href="https://detroitmi.gov/sites/detroitmi.localhost/files/2020-11/November%202020%20Election%20Summary%20Report%20Signed%20Copy.pdf">95% of voters in Detroit</a>the biggest city in Michigan and the one with probably the most African-Americans – <a href="https://data.census.gov/table/DECENNIALPL2020.P1?g=160XX00US2622000">78% of residents</a> – solid their vote for Joe Biden, the Democratic presidential candidate.</p>
<p>We are <a href="https://scholar.google.com/citations?user=k_E-AVoAAAAJ&#038;hl=en">Political Science</a> And <a href="https://scholar.google.com/citations?user=M7ha-_0AAAAJ&#038;hl=en&#038;oi=ao">sociology</a> Professors at Wayne State University in Detroit, where we teach in regards to the relationship between race, religion and politics. <a href="https://press.umich.edu/Blog/2021/09/Race-and-the-Power-of-Sermons-on-American-Politics">Our research</a> has identified two groups of African-American voters in Detroit – one that may clearly support Kamala Harris, and one other whose votes she must win if she is to win in Michigan. </p>
<h2>Celebration in Kamala&#39;s camp</h2>
<p>The African Americans more than likely to vote for Harris in November 2024 are staunch Democrats <a href="https://doi.org/10.1007/s13644-014-0206-x">who consider Trump would threaten the political progress of black people</a> towards democracy.</p>
<p>Harris may also depend on members of Detroit nonprofit organizations similar to the NAACP, Black Greek organizations and <a href="https://press.umich.edu/Blog/2021/09/Race-and-the-Power-of-Sermons-on-American-Politics">religious communities linked to interest groups</a> like for instance <a href="https://www.mosesmi.org/">MOSES</a>The <a href="https://www.facebook.com/MWROdetroit/">Michigan Welfare Law Organization</a> and the <a href="https://flhpac.org/">Fannie Lou Hamer Political Action Committee</a>.  </p>
<p>But what about black employees and poor Detroiters who&#8217;ve less close ties to the Democratic Party and are less involved in grassroots organizations that advocate for his or her interests? These people don&#39;t all the time end up in presidential elections, but as recent history has shown, they may very well be key to winning in Michigan, a vital swing state.</p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#36495c"><img decoding="async" alt="Protesters with signs reading “Detroit Cheats” and “Election Fraud”" class="lazyload" src="https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/619171/original/file-20240912-16-3js4kc.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">Supporters of Donald Trump protest in front of the TCF Center in Detroit against the vote count within the 2020 general election.</span><br />
              <span class="attribution"><a class="source" href="https://www.gettyimages.com/detail/news-photo/supporters-for-us-president-donald-trump-demonstrate-news-photo/1229491491?adppopup=true">Jeff Kowalsky/AFP via Getty Images</a></span><br />
            </figcaption></figure>
<h2>Small differences in voter turnout are essential</h2>
<p>While Detroit voters <a href="https://www.cnn.com/election/2020/results/state/michigan">helped Biden win the state</a> and the White House in 2020, that was not the case for <a href="https://www.politico.com/story/2016/12/michigan-hillary-clinton-trump-232547">Hillary Clinton in 2016</a>. </p>
<p>The difference was partly resulting from lower voter turnout.</p>
<p>In 2016 <a href="https://detroitmi.gov/sites/detroitmi.localhost/files/2018-05/official-results-nov-8-2016.pdf">95% of Detroiters who voted</a> In the presidential election, the Democratic candidate Clinton was chosen. <a href="https://www.cnn.com/election/2016/results/states/michigan">She lost Michigan by 0.2%</a> – lower than 11,000 votes. </p>
<p>One factor contributing to the several presidential election ends in Michigan between 2016 and 2020 was the lower voter turnout in Detroit in 2016 in comparison with 2020.  </p>
<p>In 2016 <a href="https://detroitmi.gov/sites/detroitmi.localhost/files/2018-05/official-results-nov-8-2016.pdf">Voter turnout in Detroit was 48.6%</a> – in comparison with <a href="https://detroitmi.gov/sites/detroitmi.localhost/files/2020-11/November%202020%20Election%20Summary%20Report%20Signed%20Copy.pdf">50.88% in 2020</a>. Detroit&#39;s higher voter turnout in 2020 helped Biden win Michigan by a margin in 2020. <a href="https://www.npr.org/2020/11/04/931398045/biden-wins-michigan-per-the-ap-putting-him-6-electoral-votes-from-presidency">Margin of lower than 3%</a>.       </p>
<p>Let&#39;s assume that 2016 and 2020 are signposts for 2024. In this case, Harris&#39; ability to win Michigan in November rests less on losing black voters to Trump than on her ability to motivate black voters in Detroit and across the state to go to the polls. This is crucial because African Americans, <a href="https://www.pewresearch.org/social-trends/2020/09/23/the-changing-racial-and-ethnic-composition-of-the-u-s-electorate/">about 13% of US voters</a>overwhelmingly vote for the Democrats of their elections.</p>
<p>In some ways, 2020 was a referendum on Trump’s handling of the COVID-19 epidemic, which has had a disproportionate impact on black Americans who <a href="https://www.kff.org/racial-equity-and-health-policy/issue-brief/covid-19-cases-and-deaths-by-race-ethnicity-current-data-and-changes-over-time/">almost twice as likely</a> than white Americans die from the virus. </p>
<p>This election also served as a referendum on Trump’s racial policies. In the summer of 2020, when the nation was embroiled in protests against anti-black police violence, Trump portrayed the protesters as <a href="https://www.forbes.com/sites/tommybeer/2021/01/06/trump-called-blm-protesters-thugs-but-capitol-storming-supporters-very-special/">Anti-Americans and criminals</a>. </p>
<p>It is smart, then, that in 2020, the overwhelming majority—over 90%—of African Americans nationwide said that <a href="https://www.pewresearch.org/dataset/july-2020-political-survey/">Concerns about racism and COVID-19</a> motivated her voice.</p>
<p>Looking ahead to the 2024 elections, the query is: Will black voter turnout in Detroit be closer to that of 2016 or 2020?  </p>
<h2>Quality of life issues in focus in 2024</h2>
<p>As of early 2024, quality of life concerns related to crime, vacant buildings and reasonably priced housing were the highest three issues Detroit residents want from their city and the U.S. government. <a href="https://outliermedia.org/wp-content/uploads/2024/06/0617_out_SurveyDMACS_Wave19Toplines.pdf">based on the Detroit Metro Area Communities Study</a>.  </p>
<p>A survey by Suffolk University and USA Today in August 2024 found that <a href="https://ropercenter.cornell.edu/ipoll/study/31122032/questions#2e4860e8-38f7-417f-b600-9dfe019de95f">About 6 out of 10 black voters in Michigan</a> They cited rising living costs, crime and health care as reasons for his or her willingness to vote.  </p>
<p>These same issues are top of mind for black voters across the country. A February 2024 Kaiser Family Foundation poll found that <a href="https://ropercenter.cornell.edu/ipoll/study/31120880">over 90% of black Americans</a> think presidential candidates should discuss the rising cost of living and health care, and three-quarters think they need to discuss protecting the Affordable Care Act.</p>
<p>The 2024 elections are a vital moment to handle these issues.   </p>
<h2>Detroit&#39;s ongoing water concerns</h2>
<p>For working-class and low-income residents of Detroit, water costs are a key cost-of-living issue. </p>
<p>As Detroit City Council attempted to repair its funds following its bankruptcy in 2013, it began to more aggressively goal residents who were behind on their water bills. The city cut off water from <a href="https://www.bridgemi.com/michigan-health-watch/detroit-says-no-proof-water-shutoffs-harm-health-get-real-experts-say">greater than 141,000 inhabitants</a> between 2013 and 2020.  </p>
<p>By 2023, 27% of Detroit households – about 170,000 people – are vulnerable to having their water shut off resulting from <a href="https://www.freep.com/story/news/local/michigan/detroit/2022/06/13/detroit-water-shut-off-moratorium-ending/9585754002/">unpaid water bills</a>The 60,000 individuals who haven&#8217;t paid their water bills owe a mean of $700.</p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#48562f"><img decoding="async" alt="Man in front of the house uses device on the lawn to shut off the water supply to the house" class="lazyload" src="https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/619178/original/file-20240912-20-olqkmy.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">A employee turns off the water supply to a house in Detroit.</span><br />
              <span class="attribution"><a class="source" href="https://www.gettyimages.com/detail/news-photo/worker-from-homrich-turns-off-water-supply-to-a-home-august-news-photo/454251826?adppopup=true">Joshua Lott via Getty Images</a></span><br />
            </figcaption></figure>
<p>In response to this crisis, local grassroots organizations, a lot of them religiously based, similar to the <a href="https://detroitwaterstories.wordpress.com/portfolio/sylvia-orduno-michigan-welfare-rights/">Michigan Welfare Law Organization</a>Community members organized to push for laws that may tie water bills to residents’ income. </p>
<p>In October 2023, Michigan Democrat State <a href="https://senatedems.com/chang/2023/10/02/transformative-water-affordability/">Senator Stephanie Chang</a> introduced quite a few bills to attain just that, however the <a href="https://www.legislature.mi.gov/Bills/Bill?ObjectName=2023-SB-0549">Bills have been left behind</a>  within the Senate Committee on Housing and Social Services. </p>
<p>A survey we conducted within the Detroit metropolitan area in April 2024 found that <a href="https://clasprofiles.wayne.edu/profile/am9398">87% of black Detroiters</a> support these bills to enhance water affordability. </p>
<p>Harris&#39; ability to attain similarly high black turnout in Michigan, particularly Detroit, as she did in 2020 could rely on whether she will articulate the federal government&#39;s plans to handle cost-of-living issues, including securing federal grants for cities like Detroit to subsidize water rates for working-class and low-income residents.  </p>
<p>Harris didn&#8217;t explicitly address the difficulty of water affordability in her speech. <a href="https://www.c-span.org/video/?538081-1/vice-president-harris-campaigns-detroit-michigan">Visiting Detroit on Labor Day</a>she told the audience that, unlike Trump, she wouldn&#8217;t impose a national sales tax on on a regular basis items. She also promised to maintain prescription drug prices reasonably priced and strengthen the Affordable Care Act.</p>
<p>Will Harris&#39; message that the price of living for Detroit residents would worsen under a Trump administration be enough to motivate black Detroit residents to vote for her? </p>
<p>This is a vital query for her 2024 campaign in Michigan, where she and Trump are in a <a href="https://projects.fivethirtyeight.com/polls/president-general/2024/michigan/">statistical tie amongst likely voters</a>.</p>
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<p><em>image credit : theconversation.com</em></p>
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		<title>Found dead within the snow – how microbes will help determine the time of death in forensic investigations under icy conditions</title>
		<link>https://bloggingthree.soflytech.com/2024/09/found-dead-within-the-snow-how-microbes-will-help-determine-the-time-of-death-in-forensic-investigations-under-icy-conditions/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Mon, 09 Sep 2024 23:14:24 +0000</pubDate>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[conditions]]></category>
		<category><![CDATA[dead]]></category>
		<category><![CDATA[death]]></category>
		<category><![CDATA[determine]]></category>
		<category><![CDATA[forensic]]></category>
		<category><![CDATA[icy]]></category>
		<category><![CDATA[investigations]]></category>
		<category><![CDATA[microbes]]></category>
		<category><![CDATA[snow]]></category>
		<category><![CDATA[time]]></category>
		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=14310</guid>

					<description><![CDATA[What happens to a body in a particularly cold environment? Does it decompose? How do these conditions affect how forensic scientists determine the person&#39;s time of death? Estimation of the time of death, also postmortem intervalis a fancy task. It plays a vital role in forensic investigations as it will possibly provide vital insights into [&#8230;]]]></description>
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<p>What happens to a body in a particularly cold environment? Does it decompose? How do these conditions affect how forensic scientists determine the person&#39;s time of death?</p>
<p>Estimation of the time of death, also <a href="https://doi.org/10.1016/j.forsciint.2015.07.024">postmortem interval</a>is a fancy task. It plays a vital role in forensic investigations as it will possibly provide vital insights into the timeline of events that led to an individual&#39;s death. This information can narrow down potential scenarios and suspects, helping to resolve crimes. </p>
<p>Quite a lot of aspects come into play on the scene of a death, from environmental conditions to the state of health of the person before death. In the past, scientists have estimated the time of death by observing postmortem physical and biological changes within the body, equivalent to stiffening, fluid retention, and cooling. </p>
<p>However, these methods are limited by their variability and dependence on external aspects. Calculating the postmortem interval became more precise with the arrival of molecular biology. But it remains to be a difficult task, especially in extremely cold weather conditions. In the primary few months after death, a frozen body often lacks obvious signs of decomposition.</p>
<p>We are forensic scientists and lead the forensic programs at <a href="https://campus.und.edu/directory/lavinia.iancu">University of North Dakota</a> and the <a href="https://scholar.google.com/citations?user=sOY9daIAAAAJ&#038;hl=it&#038;oi=ao">University of Central Lancashire</a>. We are using molecular biology and bioinformatics to develop tools to assist researchers and investigators estimate the postmortem interval more accurately. Our research, recently published in Frontiers in Microbiology, found that <a href="https://doi.org/10.3389/fmicb.2024.1392716">Investigation of the microbes involved in decomposition</a> was in a position to predict the time elapsed since death under extreme cold conditions with high accuracy.</p>
<h2>Decomposition in cold environments</h2>
<p>Our study took place in Grand Forks, North Dakota, certainly one of the <a href="https://www.thetravel.com/coldest-cities-in-the-us/">coldest cities within the United States</a>where winters are characterised by temperatures reaching <a href="https://www.weather.gov/fgf/climategraphs">-40 degrees Fahrenheit (-40 degrees Celsius)</a> and powerful winds that may reach <a href="https://www.grandforksherald.com/weather/blizzard-finley-with-winds-that-could-gust-past-50-mph-prompts-blizzard-warning-for-grand-forks-region">as much as 31 miles per hour (50 kilometers per hour)</a>.</p>
<p>In a particularly cold environment equivalent to North Dakota winters, traditional methods will not be sufficient to grasp decomposition and estimate time of death. For example, the body cools far more quickly in cold temperatures, which might distort estimates based on body temperature. </p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#6f798b"><img decoding="async" alt="Barren field covered with snow in weak sunlight" class="lazyload" src="https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/617367/original/file-20240904-16-re9qqc.JPG?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">The researchers moved their investigation to Grand Forks, North Dakota, where winters might be very harsh, on the time of death.</span><br />
              <span class="attribution"><span class="source">Lavinia Iancu</span>, <a class="license" href="http://creativecommons.org/licenses/by-sa/4.0/">CC BY-SA</a></span><br />
            </figcaption></figure>
<p>Likewise, cold environments can delay the onset and duration of rigor mortis, or stiffening of the body. The decomposition process, including the activity of insects and other scavengers that contribute to the decay of the body, can be slowed or stopped by freezing temperatures.</p>
<p>Snow is one other vital consider the study of decomposition. It can isolate a body by <a href="http://dx.doi.org/10.2307/1552029">Store residual heat</a> and its temperature becomes barely higher than that of the environment. Due to this insulating effect, the body decomposes more slowly than bodies exposed to the open air. </p>
<h2>Microbes and the time since death</h2>
<p>In extreme cold, using additional tools is essential to grasp the decomposition process and estimate the time of death. <a href="https://doi.org/10.1002/pmic.202200335">Advanced molecular techniques</a>equivalent to evaluation of the microbiome, gene expression and protein degradation, will help provide useful information in regards to the crime scene.</p>
<p>Each organism has different microbial properties that <a href="https://doi.org/10.1016/j.jflm.2021.102223">act like a fingerprint</a>The necrobiome, a community of microbes related to decaying stays, plays an important role in decay. Certain microbes are present during <a href="https://doi.org/10.1371/journal.pone.0077733">different stages of decomposition</a>which helps break down tissue and recycle nutrients. Forensic investigators can take samples of what microbes live in a dead body to make use of the composition of the microbial population to find out how way back an individual died.</p>
<p>Our study focused on identifying <a href="https://doi.org/10.3389/fmicb.2024.1392716">Common patterns of microbial changes</a> that occur during decomposition in extremely cold environments. Over a period of 23 weeks, we collected and analyzed 393 microbial samples from the within and outdoors of the noses of dead pigs that were covered in snow. Pigs decompose in an analogous option to humans and are <a href="https://doi.org/10.1007/s00414-019-02074-5">often utilized in forensic research</a>We developed models to estimate the postmortem interval by pairing microbial genetic data with environmental data equivalent to snow depth and outdoor temperature.</p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#364652"><img decoding="async" alt="Person puts swab in the nose of a dead pig lying on its side behind a fence in the snow" class="lazyload" src="https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/617362/original/file-20240904-18-zlj4hw.JPG?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">The researchers collect samples from the within and outdoors of the noses of dead pigs.</span><br />
              <span class="attribution"><span class="source">Lavinia Iancu</span>, <a class="license" href="http://creativecommons.org/licenses/by-nd/4.0/">CC BY-ND</a></span><br />
            </figcaption></figure>
<p>Overall, we found that the bacterial species <a href="https://doi.org/10.3389/fmicb.2024.1392716">And </a> can best predict the time after death under extreme winter conditions, namely as much as six months after death, with an error margin of just over nine days. </p>
<p>We found that several types of bacteria are most abundant at different times. For example, levels increase from five weeks after death and are most abundant at ten weeks, while they increase between five and nine weeks and peak at 18 weeks. </p>
<h2>Improving forensics</h2>
<p>Death is commonly an uncomfortable topic to discuss. However, from a forensic perspective, techniques and methods to find out an individual&#39;s death will help bring justice and peace to family members.</p>
<p>Our study found that decomposition doesn&#8217;t stop completely even in cold environments. Studying the microenvironment – ​​the local conditions across the body, including temperature, humidity and microbial activity – can provide vital information in regards to the decomposition process. The major microbial species we identified served as <a href="https://doi.org/10.3389/fmicb.2024.1392716">Biomarkers of death</a>allowing us to develop time-of-death models that help researchers overcome the constraints of purely visual examination of stays.</p>
<p>Microbes can grow to be an important piece of the puzzle in solving a death, helping to ascertain more precise timelines even under extreme conditions.</p>
</p></div>
<p><em>image credit : theconversation.com</em></p>
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		<title>Arrest student protesters, wait or negotiate? Colleges can use &#039;damage ladder&#039; to find out appropriate response to Gaza protests on campus</title>
		<link>https://bloggingthree.soflytech.com/2024/07/arrest-student-protesters-wait-or-negotiate-colleges-can-use-damage-ladder-to-find-out-appropriate-response-to-gaza-protests-on-campus/</link>
		
		<dc:creator><![CDATA[chandankumarsoft]]></dc:creator>
		<pubDate>Sat, 27 Jul 2024 22:06:13 +0000</pubDate>
				<category><![CDATA[News]]></category>
		<category><![CDATA[39damage]]></category>
		<category><![CDATA[arrest]]></category>
		<category><![CDATA[campus]]></category>
		<category><![CDATA[colleges]]></category>
		<category><![CDATA[determine]]></category>
		<category><![CDATA[Gaza]]></category>
		<category><![CDATA[ladder39]]></category>
		<category><![CDATA[negotiate]]></category>
		<category><![CDATA[protesters]]></category>
		<category><![CDATA[protests]]></category>
		<category><![CDATA[response]]></category>
		<category><![CDATA[student]]></category>
		<category><![CDATA[wait]]></category>
		<guid isPermaLink="false">https://bloggingthree.soflytech.com/?p=10185</guid>

					<description><![CDATA[The summer brought an end, for now, to the anti-war protests that rocked college campuses across the United States through the spring semester of 2024. However, the Israeli assault on Gaza continues, and student protests could erupt again in the autumn, especially if the presidential election heightens political tensions. Once again, college presidents across the [&#8230;]]]></description>
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<p>The summer brought an end, for now, to the anti-war protests that rocked college campuses across the United States through the spring semester of 2024. However, the Israeli assault on Gaza continues, and student protests could erupt again in the autumn, especially if the presidential election heightens political tensions.</p>
<p>Once again, college presidents across the United States could also be forced to make difficult and controversial decisions: Should they tolerate youthful civil disobedience, suppress dissent, or seek peaceful solutions?</p>
<p>My research on <a href="https://ash.harvard.edu/articles/campus-protests-and-police-force-an-ethical-framework/">civil disobedience, deliberation and democracy</a> offers a possibility to investigate this necessary query.</p>
<h2>Threatening or peaceful protest?</h2>
<p>Between November 2023 and May 2024, 1000&#8217;s of scholars <a href="https://nonviolentactionlab.shinyapps.io/palestine-protest-dashboard/">greater than 120</a> Universities and colleges across the country arrange camps to protest Israel&#39;s war against Hamas in Gaza. They also condemned their universities&#39; investments and other ties to Israel, which they viewed as support for that war.</p>
<p>At some campuses, including Columbia, UC Irvine and Portland State University, students occupied buildings and sometimes <a href="https://www.opb.org/article/2024/05/14/portland-state-university-community-reaction-next-steps/%22%22">Vandalized facilities</a>which led to widespread condemnation. </p>
<p>However, most student camps were peaceful and non-violent. <a href="https://ash.harvard.edu/programs/crowd-counting-consortium/">Crowd Counting Consortium</a>a Harvard Kennedy School project that collects data on protests worldwide reports that protesters damaged property on only 10 campuses. Yet police arrested protesters at 60 schools. Those university presidents who asked either campus police or local police departments to intervene said they&#8217;d <a href="https://www.npr.org/2024/05/02/1248634146/columbia-university-mayor-eric-adams-nypd-student-arrests">Protecting community members from violence</a> and to make sure teaching, learning and research. </p>
<p>Nevertheless, half of all anti-war protests on campus dispersed with none arrests. <a href="https://www.bostonglobe.com/2024/04/30/metro/protesters-clear-encampment-brown-university-after-reaching-compromise-divestment/">Brown</a>, <a href="https://www.northwestern.edu/leadership-notes/2024/agreement-on-deering-meadow.pdf">Northwestern</a>, <a href="https://newbrunswick.rutgers.edu/sites/default/files/2024-05/response_05022024_2.pdf">Rutgers</a>, <a href="https://ktvz.com/cnn-regional/2024/05/01/police-wont-break-up-pro-palestinian-protest-at-johns-hopkins-barring-any-credible-threat-of-violence/">Johns Hopkins University</a> and other university presidents sought de-escalation, negotiations and other peaceful ways to resolve the conflict. After the administration agreed to measures comparable to transparency in investments, support for Palestinian students and academics, or easing sanctions against protesters, the scholars voluntarily dismantled their tents and went to check for final exams. </p>
<p>So when, if ever, should universities use police to combat student protests? </p>
<h2>“Head of Damage”</h2>
<p>The answer will depend on how disruptive the protests are. </p>
<p>Here is a scale to evaluate some levels of harm. It relies on recommendations from lawyers on the University of California <a href="https://campusprotestreport.universityofcalifornia.edu/">Chris Edley and Charles Robinson</a> after an attack of <a href="https://theaggie.org/2021/11/18/the-uc-davis-pepper-spray-incident-10-years-later/">aggressive police motion</a> against protesters at UC Davis in 2011.</p>
<p><iframe id="SQf7N" class="tc-infographic-datawrapper" src="https://datawrapper.dwcdn.net/SQf7N/3/" height="400px" width="100%" style="border: 0;" scrolling="no" frameborder="0"></iframe></p>
<p>The protest harm scale ranges from Level 1 &#8211; civil disobedience without disruption &#8211; to Level 4, which indicates a violent protest that poses an imminent threat to public safety. It provides a standard benchmark for many who disagree about whether the coed protesters are right or unsuitable, just or hateful, to collectively assess the extent of harm and disruption their protests are causing. </p>
<p>Opinions often differ on this issue. For example, through the anti-war rebellion on Harvard&#39;s campus within the spring of 2024, students and school expressed very different opinions about how disruptive the rebellion was. </p>
<p>“They set up forty tents, draped a keffiyeh over the iconic John Harvard statue, blared music from a loudspeaker, hoisted Palestinian flags over the university hall and sang through megaphones,” the professors said. <a href="https://www.bostonglobe.com/2024/04/29/opinion/gaza-college-protest-ban-steven-pinker-jeffrey-flier/">Jeff Flier and Steven Pinker</a> wrote within the Boston Globe. Their comments suggest that they found the Harvard camp unbearably disruptive—a level 3 on a scale of 1 to 4.</p>
<p>However, many students found the occupation of Harvard Yard to be unobtrusive – more like Level 1.</p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.71087533156499%;--background-color:#504a35"><img decoding="async" alt="About half a dozen tents have been set up on Harvard&#39;s campus, and young people are milling around in them." class="lazyload" src="https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/606989/original/file-20240715-17-rnsw7n.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">Unbearably disturbing? Depends on who you ask. The anti-war camp in Harvard Yard, April 25, 2024.</span><br />
              <span class="attribution"><a class="source" href="https://newsroom.ap.org/detail/Israel-Palestinians-Campus-Protests/a6b182e69dea4811b5672b65851de7fd/photo?Query=harvard%20encampment&#038;mediaType=photo&#038;sortBy=arrivaldatetime:desc&#038;dateRange=Anytime&#038;totalCount=23&#038;currentItemNo=4">Ben Curtis/AP</a></span><br />
            </figcaption></figure>
<p>The Harvard Crimson interviewed 40 freshmen who lived on campus near the camp. &#8220;Almost all said that the camp did not significantly change their daily lives or prevent them from learning,&#8221; the <a href="https://www.thecrimson.com/article/2024/5/2/harvard-yard-encampment-freshmen-dorms/">Newspaper reports</a>One student who “had a view of the camp from her dorm” compared the noise level to that of the tourists milling across the yard.</p>
<p>At other schools, teachers, administrators and students also got here to significantly different assessments of their camps within the Gaza Strip. </p>
<p>After armed police used chemical weapons and electric shocks to disperse protesters at Emory University, <a href="https://www.11alive.com/article/news/local/emory-university-no-confidence-vote-president-greg-fenves/85-16a73eff-172e-4bc6-ba9c-e0f73ad9e1cc">Finally, no less than 28 people were arrested</a>wrote University President Gregory Fenves <a href="https://president.emory.edu/communications/2024/04/april-26-yesterdays-protests.html">in a letter</a> that “we will not tolerate vandalism, violence, or any attempt to disrupt our campus.” </p>
<p>Soon after <a href="https://atlantaciviccircle.org/2024/05/03/emory-college-faculty-vote-no-confidence-university-president-student-protests/">The faculty voted overwhelmingly</a> “Distrust” of Fenves, <a href="https://www.11alive.com/article/news/local/emory-university-no-confidence-vote-president-greg-fenves/85-16a73eff-172e-4bc6-ba9c-e0f73ad9e1cc">described the camp as a “peaceful demonstration”</a> There is “no evidence of violence” and “no disruption to teaching and research operations”. </p>
<p>There was also disagreement concerning the level of disturbance at which police intervention can be obligatory. </p>
<p>Some administrators felt that any violation of university rules warranted police intervention, even a Level 1 tent encampment that didn&#8217;t block access to offices or classrooms or make much noise. Dartmouth College President Sian Leah Beilock, for instance, called on police to clear protesters. <a href="https://www.nytimes.com/2024/05/13/us/dartmouth-campus-protests-police-beilock.html">only two hours</a> after organising tents in violation of campus rules prohibiting the development of buildings. </p>
<p>In many private corporations, that is standard practice. If Meta employees arrange protest tents on their campus, hardly anyone can be surprised or dismayed if the police immediately got here and cleared them away.</p>
<p>But Harvard Police Chief Victor Clay set the bar for an arrest much higher – to about Level 4. He told the <a href="https://www.thecrimson.com/article/2024/4/27/harvard-police-chief-encampment-peaceful/">Crimson in April 2024</a> that only “significant property damage or physical violence of any kind” would justify the detention of scholars. Baltimore police were <a href="https://ktvz.com/cnn-regional/2024/05/01/police-wont-break-up-pro-palestinian-protest-at-johns-hopkins-barring-any-credible-threat-of-violence/">equally hesitant to concentrate on</a> what it called a “valid” camp at Johns Hopkins University. </p>
<p>The management of each universities ultimately dissolved their camps without police motion.</p>
<h2>Using the dimensions</h2>
<p>The harm ladder cannot settle disagreements about whether students are right or unsuitable. It cannot even fully resolve subjective opinions about how harmful their protests are. But it may help move beyond the simplistic and sometimes incorrect judgments that characterised much of the discussion concerning the spring 2024 campus protests. </p>
<p>One side shouted: “Students broke the rules, call the police.” Others condemned any use of violence against demonstrators. </p>
<p>In many cases, the people calling for police motion didn&#8217;t just like the protesters&#39; criticism of Israel. Many university presidents felt enormous pressure from university boards, Congress, alumni, and advocacy groups to quell the protests. </p>
<p>On the damage scale, none of those points justify a call to the police. </p>
<figure class="align-center zoomable">
<div class="placeholder-container" style="--aspect-ratio-percent:66.04774535809018%;--background-color:#562b29"><img decoding="async" alt="Night shot of police officers in riot gear crowding around people lying on the ground" class="lazyload" src="https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;rect=44%2C22%2C5000%2C3300&#038;q=45&#038;auto=format&#038;w=754&#038;fit=clip" srcset="https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=1 600w, https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=2 1200w, https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=600&#038;h=400&#038;fit=crop&#038;dpr=3 1800w, https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=45&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=1 754w, https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=30&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=2 1508w, https://images.theconversation.com/files/606993/original/file-20240715-17-pr5fzh.jpg?ixlib=rb-4.1.0&#038;q=15&#038;auto=format&#038;w=754&#038;h=503&#038;fit=crop&#038;dpr=3 2262w" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px"></div><figcaption>
              <span class="caption">The Los Angeles Police Department cracks down on pro-Palestinian protesters on the UCLA campus in Los Angeles on May 2, 2024.</span><br />
              <span class="attribution"><a class="source" href="https://newsroom.ap.org/detail/CampusProtestsTheReckoning/d06b50f92676438da7f562dbafd13b68/photo?Query=(datelinelocation.countryname:%22united%20states%22)%20AND%20%20(police%20campus%20gaza)%20&#038;mediaType=photo&#038;sortBy=arrivaldatetime:desc&#038;dateRange=Anytime&#038;totalCount=19&#038;currentItemNo=2">Jae C. Hong/AP</a></span><br />
            </figcaption></figure>
<p>The threshold for <a href="https://docs.google.com/document/d/1GOR_uEixyyeBst3rzv4avgw6Eeir8ROYSbZQQcEmjCA/edit">violent termination of consultation</a> at educational institutions is high for good reason. Reason and discussion as methods of resolving disagreements are embedded within the DNA of universities and colleges, which isn&#8217;t the case at corporations or government agencies.</p>
<p>Civil disobedience is by its nature partly persuasive and partly disruptive. Police actions only exert coercion and shut down dialogue. And arresting students has serious consequences, including expulsion from school, criminal records, loss of monetary aid, and potentially reduced job prospects. </p>
<p>But sometimes police intervention is obligatory, depending on the dimensions of the damage. If and when protests endanger people, disrupt necessary school activities, or cause other serious harm, then &#8211; and only then &#8211; is it time to call the police. </p>
<p>Dialogue, learning and debate within the pursuit of truth and wisdom are among the many core values ​​of a university. Flash grenades, stun guns and human shields contradict these values.</p>
</p></div>
<p><em>image credit : theconversation.com</em></p>
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